๐ย Les Diablerets | Ithemyc Project โ Annual Meeting
The Ithemyc Project Annual Meeting is currently taking place in Les Diablerets, marking an advanced phase of the project in which discussions are increasingly focused on concrete outputs and practical applications.
The afternoon session is dedicated to an update on in silico testing within WP3, including a presentation and live demonstration of the UISS model. The session highlights how the platform is currently employed to perform in silico experiments aimed at evaluating and comparing different therapeutic strategies against mycobacterial infections.
๐ง In silico testing with the UISS model
The live demonstration showcases the capability of the UISS model to simulate the dynamic interactions between the immune system, the pathogen, and therapeutic interventions. By running virtual treatment scenarios, the platform enables the assessment of treatment effects over time, the comparison of single-agent therapies versus combination strategies, and the identification of potentially optimal approaches prior to experimental or clinical validation.
๐ From model development to decision support
This update illustrates the transition of UISS from a research model to an operational decision-support tool, capable of generating quantitative insights to guide treatment prioritization and inform downstream experimental and clinical activities within the Ithemyc Project.
Overall, this represents a key step forward in translating in silico modelling into actionable knowledge for the development of innovative and effective therapeutic strategies.
